Why was half the Fairlie Group present at the Australian Synchrotron in Melbourne this month?

26 October, 2014

The new ARC Centre of Excellence in Advanced Molecular Imaging is integrating the research activities of physicists, structural biologists, chemists and immunologists in order to better understand the molecular basis of immunity and disease. The Australian Synchrotron is providing the power necessary to see into the secrets of immunology that have to date evaded researchers in the field. Our cooperative studies can give a more detailed picture on how the immune system works at the atomic, molecular, macromolecular, cellular and animal levels and this is essential in 21st century efforts to combat major diseases.

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New National Health And Medical Research Council Grants

17 October, 2014

Congratulations to Dr Abishek Iyer, Dr Rink-Jan Lohman, Dr Jacky Suen and Prof David Fairlie from the Fairlie Group who are chief investigators on three new research grants:

(1) Targeting Protease Activated Receptor 2 In Immunometabolism And Obesity

(2) Downsizing A Human Protein To Modulate Inflammatory Diseases

(3) Modulating Inflammatory and Fibrogenic Pathways in Kidney Disease using a novel antagonist of     Protease-Activated-Receptor-2

Launch of the ARC Centre of Excellence in Advanced Molecular Imaging

15 October, 2014

Researchers from the Fairlie Group travelled to Melbourne for the official launch of this new ARC Centre of Excellence at Monash University and for a mini-symposium at the Australian Synchrotron involving the Centre’s researchers.  This begins a seven year collaboration between physicists, chemists, structural biologists and immunologists aimed at understanding the molecular basis of immunity.

http://www.uq.edu.au/news/article/2014/10/imaging-centre-unravel-secrets-of-immune-system

PhD Student News

1 October, 2014

Congratulations to PhD student Daniel Nielsen for winning a Graduate School International Travel Award from a field of over 100 applicants. Dan will use the award to present at the 249th national meeting of the American Chemical Society in Denver, Colorado and to visit collaborators at Pfizer in Boston.

Congratulations to new PhD student Yuhong Jiang for winning a Chinese Scholarship Council award to commence studies at the University of Queensland.

Two recent publications recommended by F1000

Two of our newest 2014 publications in American Chemical Society journals have been selected for F1000Prime after recommendations (as being of special significance in their fields) by members of the Faculty of 1000.

Cyclic Penta- and Hexa- Leucine Peptides without N-Methylation Are Orally Absorbed” American Chemical Society Medicinal Chemistry Letters, 2014 (DOI: 10.3410/f.718535035.793498861) by Dr Tim Hill and colleagues. Faculty of 1000Prime citation (http://f1000.com/prime/718535035).

Stereoelectronic Effects Dictate Molecular Conformation and Biological Function of Heterocyclic Amides” Journal of the American Chemical Society, 2014 (DOI: 10.3410/f.718522891.793498839) by Dr Robert Reid and colleagues. Faculty of 1000Prime citation (http://f1000.com/prime/718522891).

Lysine acetylation in sexual stage malaria parasites is a target for antimalarial small molecules

Lysine acetylation in sexual stage malaria parasites is a target for antimalarial small molecules
Trenholme K, Marek L, Duffy S, Pradel G, Fisher G, Hansen FK, Skinner-Adams TS, Butterworth A, Julius Ngwa C, Moecking J, Goodman CD, McFadden GI, Sumanadasa SD, Fairlie DP, Avery VM, Kurz T, Andrews KT

Antimicrob Agents Chemother 2014 58 3666-3678.